Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.

Saccharomyces boulardii vs L. reuteri

On Reddit, owners rate Saccharomyces boulardii higher overall (4.0 vs 3.5). Scores summarize self-reported experiences and are not evidence that either will work for you.

	Saccharomyces boulardii	L. reuteri
Type	capsules	tablets or homemade yogurt
GutVerdict score	4.0	3.5
Owner sentiment	3.6	3.6
Recommendations	3.7	1.0
Tolerability	4.8	4.7
Owner comments	478	278
Rated comments	177	119
Unwanted effects reported	8%	9%
Top praise	Dose & timing, Urgency & loose stools	Dose & timing, Bloating & gas
Top complaints	Side effects, Urgency & loose stools	Side effects, Bloating & gas

By symptom

Context	Saccharomyces boulardii	L. reuteri
IBS-C & constipation	16 of 21 positive	8 of 12 positive
IBS-D & loose stools	28 of 32 positive	0 of 3 positive
Bloating & gas	24 of 26 positive	16 of 21 positive
SIBO	65 of 87 positive	64 of 81 positive
After antibiotics	39 of 43 positive	6 of 10 positive
Pain & cramping	13 of 16 positive	5 of 8 positive

Here is how to read a probiotic label by strain. For the full picture, see our gut supplement ratings built from Reddit owner comments. For quick shortlists by symptom, see which gut supplements IBS communities rate highest.

What owners say about Saccharomyces boulardii

4/5 Cost
“I've tolerated taking Florastor 3x a day during antibiotics.”

owner comment via r/SIBO · 2026-10-04 · 6 upvotes

1/5
“Boulardii followed by a month of daily lentils solved 3 years of gut imbalance for me.”

owner comment via r/Microbiome · 2026-09-28 · 12 upvotes

4/5
“Just added S Boulardii, which I previously tried and reacted to but now doing much better on it.”

owner comment via r/SIBO · 2026-05-15 · 10 upvotes

Full Saccharomyces boulardii page →

What owners say about L. reuteri

4/5
“I used that when I first started making Reuteri yogurt now I am using Oxiceutics which a lot of people suspect is the BioGaia strains just not named.”

owner comment via r/SIBO · 2026-01-19 · 27 upvotes

5/5
“I also swear by taking a Reuteri supplement for improving pooping.”

owner comment via r/IBS · 2025-12-29 · 8 upvotes

4/5 Bloating & gas
“Try L Reuteri, I use biogaia gastrus - there’s a study done on it that shows it helps reduce methane, in some patients it cleared their methane completely.”

owner comment via r/SIBO · 2026-06-08 · 8 upvotes

Full L. reuteri page →

More detail: S. boulardii side effects

Talk to a doctor or pharmacist before switching or combining supplements, particularly if you take other medicines.