Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.
Magnesium · capsules or tablets

Magnesium glycinate: What People With IBS Report on Reddit

Magnesium glycinate illustration

Illustration, not a product photo.

Magnesium bound to glycine; better absorbed and usually milder on the bowel than citrate or oxide.

3.7 GutVerdict score

264 owner comments (108 with a clear rating) from r/SIBO, r/IBS, r/Constipation, r/Microbiome, r/Supplements, November 2025 to October 2026. Top 70% of the 36 rated supplements.

Owner sentiment3.7
Recommendations1.9
Tolerability4.7
ValueNot rated

Value is not rated: the example products differ too much in dose to compare cost fairly. How we score.

The short version

Magnesium glycinate is rated below most supplements we track: 3.7/5. Of 108 rated owner comments, 88 were positive, 5 mixed and 15 negative; 8 mention an unwanted effect. People talk most about regularity and side effects.

Reddit comments are self-reported and unverified. They tell you what people noticed, not whether a supplement works or is safe for you.

What it is

Safety and interactions

Supplements can interact with medicines. Talk to a doctor or pharmacist first, especially if you are pregnant, take prescription medicine, or have red-flag symptoms. See supplement safety and interactions.

Reports by symptom

ContextRated owner commentsPositiveNegativeUnwanted effects
SIBO443851
IBS-C & constipation383140
Pain & cramping171420
Bloating & gas9442
IBS-D & loose stools8352
After antibiotics4210

What Reddit owners say

Commonly praised

  • Regularity: 11 owner comments
  • Pain & cramping: 4 owner comments
  • Bloating & gas: 2 owner comments

Common complaints

  • Side effects: 7 owner comments
  • Bloating & gas: 3 owner comments
  • Urgency & loose stools: 1 owner comment
4/5

“Manage stress (I take L theanine and magnesium glycinate and it’s helped me to have a calmer response)”

owner comment via r/Microbiome · 2026-02-05 · 16 upvotes
4/5

“I take 600 mg a day of Magnesium bisglycinate for headaches and sleep.”

owner comment via r/SIBO · 2026-03-19 · 12 upvotes
5/5 Side effects

“I have to take it with food so it doesn’t upset my stomach, but other than magnesium glycinate, it has been the most life changing supplement that I’ve found.”

owner comment via r/Supplements · 2026-09-01 · 2 upvotes
2/5 Side effects

“magnesium bisglycinate (140 mg) works relatively well for me.”

owner comment via r/SIBO · 2026-02-04 · 6 upvotes
2/5 Side effectsUrgency & loose stools

“I started taking his supplement (Cool is the one he recommends for diarrhea) which includes Thiamine (Allithiamine) along with Magnesium Glycinate, about a month ago and have only had one episode of diarrhea since and that was the day I…”

owner comment via r/IBS · 2026-09-19 · 4 upvotes
+30 more owner comments
4/5

“What helped me was magnesium glycinate and Galieve Forte at night”

owner comment via r/Microbiome · 2026-08-04 · 7 upvotes
4/5

“For me, it’s back to L-reuteri supplement, ginger and artichoke capsules and occasional magnesium glycinate.”

owner comment via r/Microbiome · 2025-11-21 · 5 upvotes
4/5

“When I started taking Magnesium glycinate I started going to the toilet more and it helped my symptoms.”

owner comment via r/SIBO · 2026-07-28 · 5 upvotes
3/5 Side effects

“Almost same what I’ve faced, what I can tell you that you have to be very careful of what you are eating, try Low FODMAP, it worked for me doing low fodmap diet for 3 months and taking magnesium glycinate daily at night + glutamine 5 g…”

owner comment via r/IBS · 2026-06-30 · 1 upvotes
4/5

“I also take magnesium glycinate. One thing out of the ordinary that actually helps is a brownie mix that you get at the grocery store is Ghiralldi. I know it’s spelled wrong.”

owner comment via r/Constipation · 2025-12-02 · 3 upvotes
5/5

“What works for me is magnesium glycinate from pure encapsulations) game changer”

owner comment via r/Constipation · 2026-08-17 · 3 upvotes
4/5

“To regulate the minerals I mix small amounts of Liquid IV in my water and take mag glycinate at night.”

owner comment via r/Constipation · 2026-10-03 · 3 upvotes
4/5 Bloating & gas

“Also, I started taking magnesium glycinate and it helps SO MUCH with the bloating.”

owner comment via r/IBS · 2026-07-26 · 3 upvotes
4/5

“I also started taking magnesium glycinate and feel that the combination is helping.”

owner comment via r/SIBO · 2025-11-13 · 3 upvotes
4/5

“I tried for a long time to let my body do the work & I just took Mag Glycinate Complex, it helped, but my stool gets too hard w/o it.”

owner comment via r/Constipation · 2026-01-02 · 2 upvotes
4/5

“Mag gly will help recovery best when in a severe deficiency, its absorbed best.”

owner comment via r/Constipation · 2026-01-16 · 2 upvotes
5/5 Regularity

“Yes I can't eat oats either I take magnesium glycinate ( 2 tablets) every evening and I'm no longer constipated which is amazing for me as I have suffered with constipation all my life I also have neurogenic bowel from MS so the fact that…”

owner comment via r/Constipation · 2026-03-16 · 2 upvotes
4/5

“Different gastroenterologist and no change until i started taking magnesium glycinate.”

owner comment via r/Constipation · 2026-03-21 · 2 upvotes
3/5 Regularity

“yeah glycinate didn't do much for my constipation either until I switched to meo nutrition magnesium glycinate.”

owner comment via r/Constipation · 2026-04-03 · 2 upvotes
4/5 Pain & crampingRegularity

“I tried the sea moss probiotic gut health chews ( I use Force Factor chews) and the Magnesium Glycinate/Citrate supplement chews (Force Factor too) and it has helped so much.”

owner comment via r/IBS · 2026-02-20 · 2 upvotes
4/5

“Magnesium Glycinate has helped me.”

owner comment via r/IBS · 2026-03-10 · 2 upvotes
4/5

“I now take a multivitamin, D3+K2, a B complex, fish oil, and magnesium glycinate.”

owner comment via r/IBS · 2026-04-12 · 2 upvotes
5/5

“If i take a little too much mag glycinate that can give me issues but I do know potassium/magnesium balance can be a game changer for some.”

owner comment via r/IBS · 2026-09-05 · 2 upvotes
4/5

“That said, taking magnesium glycinate nightly has helped me for constipation.”

owner comment via r/IBS · 2026-09-17 · 2 upvotes
2/5

“Also I always take it with meals, get enough magnesium (about 370 mg/day of magnesium glycinate, sometimes less) and try to sleep well the night before.”

owner comment via r/Microbiome · 2026-02-14 · 2 upvotes
4/5

“few things helped me during a nightmare year like that - magnesium glycinate before bed, box breathing when things spike, and Bioligent Adrenal Adapt for the adaptogens since rhodiola actually helps regulate cortisol levels.”

owner comment via r/SIBO · 2026-03-01 · 2 upvotes
4/5

“210mg of Magnesium Glycinate 2x/day with food, once with breakfast, once after dinner.”

owner comment via r/SIBO · 2026-03-28 · 2 upvotes
4/5

“Some other things that helped moved the needle were hot 1/2lemon+acv+sea salt in water every morning, daily kiwis (before meals to avoid fermentation), magnesium glycinate+citrate at night, 3L warm water throughout the day, nightly castor…”

owner comment via r/SIBO · 2026-03-29 · 2 upvotes
4/5

“Magnesium glycinate has been a big help for me, I noticed I seemed to be having deficiency symptoms and with magnesium controlling muscle contractions and what not it made sense, it helped in a lot of ways!”

owner comment via r/SIBO · 2026-08-13 · 2 upvotes
4/5

“Going hardcore carnivore for a month and then keto really helped me, alongside magnesium glycinate, vitamin d3+k2 and Kijimea probiotics, the magnesium is a huge part for keeping things moving and getting muscles working right”

owner comment via r/SIBO · 2026-09-04 · 2 upvotes
4/5

“Magnesium bisglycinate tablets at night helped me relax a bit and feel sleepy.”

owner comment via r/SIBO · 2026-09-26 · 2 upvotes
4/5 Pain & cramping

“Magnesium glycinate at night (up to 360mg) helps me with the joint and muscle pain.”

owner comment via r/SIBO · 2026-10-27 · 2 upvotes
4/5 Regularity

“for energy and digestion, maybe have her look into magnesium glycinate before bed, it helped me alot with sleep quality and regularity”

owner comment via r/Supplements · 2026-06-03 · 2 upvotes
4/5 GentleSide effects

“magnesium glycinate gave me diarrhoea even though they say it’s easy on the stomach.”

owner comment via r/Supplements · 2026-10-03 · 2 upvotes
4/5 Regularity

“One of the things I found that helps me is taking magnesium glycinate.”

owner comment via r/Constipation · 2026-01-15 · 1 upvotes

Example products

These are examples of Magnesium glycinate products sold on Amazon. They are not ranked by Reddit and the score above is for the ingredient, not a specific product. Check the label for dose and other ingredients.

Example product · not Reddit-scored

Pure Encapsulations Magnesium (Glycinate), 90 Capsules

$27.00 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.
Example product · not Reddit-scored

Nature Made Magnesium Glycinate 200 mg per Serving, 60 Capsules

$11.70 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.
Example product · not Reddit-scored

THORNE Magnesium Glycinate, Chelated Magnesium Supplement, 90 Capsules

$26.00 on Amazon (price as of 2026-11-03). Prices change; check Amazon for the current price.

Research to read

Published studies (we list them so you can read the evidence yourself; inclusion is not an endorsement):

FAQ

What do people with IBS say about Magnesium glycinate on Reddit?

Across 264 Reddit comments from people who say they have used it, 88 of 108 rated comments were positive and 15 negative, for a GutVerdict score of 3.7/5. These are self-reported experiences, not clinical evidence.

Do people report side effects with Magnesium glycinate?

8 of 108 rated owner comments (7%) describe an unwanted effect such as gas, bloating or an upset stomach. Check the safety notes on this page and ask a doctor or pharmacist before starting.

Who talks about Magnesium glycinate most?

Most rated owner comments come from people in r/SIBO and others who mention SIBO (44 comments, 38 positive).

Is Magnesium glycinate scored on clinical evidence?

No. The score summarizes Reddit owner comments only. Factual statements on this page link to NIH or PubMed sources, and nothing here is medical advice.

Related supplements

Magnesium citrate illustration
Magnesium

Magnesium citrate

4.0 (843 owner comments)
RegularityPain & cramping

“Today I would take some magnesium citrate, because wherever is fermenting in your gut needs to be released not stuck up inside of you.”

What owners report →
Magnesium oxide illustration
Magnesium

Magnesium oxide

4.0 (279 owner comments)
RegularityBloating & gas

“Now at 32 I have not had an attack like this in almost a year whilst taking 400mg of magnesium oxide every night before bed..”

What owners report →
Digestive enzymes illustration
Digestive enzymes

Digestive enzymes

4.3 (809 owner comments)
Bloating & gasPain & cramping

“I began to take 1 capsule before each meal together with digestive enzymes and my symptoms lessened by about 70-80% in a few weeks.”

What owners report →

Comparisons: Magnesium citrate vs Magnesium glycinate

Last updated 2026-11-03. Mentions scanned: 636 in 502 threads.