Medical disclaimer: GutVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you are pregnant, take medicines, or have a medical condition. New, severe or worsening symptoms (such as blood in the stool, weight loss, fever, or night-time symptoms) need a doctor, not a supplement. Full disclaimer.

L-glutamine vs Zinc carnosine

On Reddit, owners rate L-glutamine higher overall (4.0 vs 3.7). Scores summarize self-reported experiences and are not evidence that either will work for you.

L-glutamineZinc carnosine
Typepowder or capsulescapsules
GutVerdict score4.03.7
Owner sentiment3.63.7
Recommendations3.62.4
Tolerability4.74.6
Owner comments456108
Rated comments16837
Unwanted effects reported9%8%
Top praiseDose & timing, Bloating & gasDose & timing, Fast-acting
Top complaintsSide effects, Dose & timingSide effects, Bloating & gas

By symptom

ContextL-glutamineZinc carnosine
IBS-C & constipation15 of 21 positive3 of 5 positive
IBS-D & loose stools18 of 22 positive3 of 3 positive
Bloating & gas19 of 26 positive5 of 7 positive
SIBO63 of 88 positive18 of 25 positive
After antibiotics12 of 16 positive2 of 3 positive
Stool form3 of 3 positiveToo few comments
Pain & cramping8 of 13 positiveToo few comments

What owners say about L-glutamine

4/5

“My condition improved when I started to take Glutamine in the morning and one banana before bed.”

owner comment via r/IBS · 2026-01-26 · 13 upvotes
2/5 Side effects

“Repair phase was GI revive but something in it gave me heartburn and nausea, so now I do the zinc carnosine and straight glutamine and it's been working well.”

owner comment via r/SIBO · 2026-07-14 · 10 upvotes
4/5

“L glutamine is good but it can be hit or miss for people with overgrowths, instead i'd focus on other tools for the gut lining like zinc l carnosine, quercetin, boswellia and a few others,”

owner comment via r/SIBO · 2026-01-22 · 9 upvotes

Full L-glutamine page →

What owners say about Zinc carnosine

2/5 Side effects

“Repair phase was GI revive but something in it gave me heartburn and nausea, so now I do the zinc carnosine and straight glutamine and it's been working well.”

owner comment via r/SIBO · 2026-07-14 · 10 upvotes
5/5

“Yes...zinc carnosine has been a gamechanger for me.”

owner comment via r/Microbiome · 2026-02-27 · 6 upvotes
4/5

“Lately, I've been feeling a bit better by taking Astralagus extract, black goat extract, L-glutamine, Kidney supplements, Zinc carnosine.”

owner comment via r/SIBO · 2026-09-13 · 4 upvotes

Full Zinc carnosine page →

More detail: L-glutamine dosage and timing

Talk to a doctor or pharmacist before switching or combining supplements, particularly if you take other medicines.