L-glutamine
“My condition improved when I started to take Glutamine in the morning and one banana before bed.”
What owners report →
Illustration, not a product photo.
Early cow milk rich in antibodies and growth factors, sold dried.
80 owner comments (37 with a clear rating) from r/SIBO, r/Microbiome, r/IBS, r/Constipation, r/Supplements, November 2025 to October 2026. Top 84% of the 36 rated supplements.
Value is not rated: the example products differ too much in dose to compare cost fairly. How we score.
Bovine colostrum is rated below most supplements we track: 3.6/5. Of 37 rated owner comments, 28 were positive, 3 mixed and 6 negative; 3 mention an unwanted effect. People talk most about bloating & gas and side effects.
Reddit comments are self-reported and unverified. They tell you what people noticed, not whether a supplement works or is safe for you.
See what owners report about gut supplements for cramping. See what owners report about gut supplements for bloating. Reddit owners also rank supplements by SIBO reports.
Supplements can interact with medicines. Talk to a doctor or pharmacist first, especially if you are pregnant, take prescription medicine, or have red-flag symptoms. See supplement safety and interactions.
| Context | Rated owner comments | Positive | Negative | Unwanted effects |
|---|---|---|---|---|
| SIBO | 21 | 16 | 5 | 2 |
| Bloating & gas | 9 | 5 | 3 | 1 |
| Pain & cramping | 4 | 3 | 1 | 0 |
4/5“I eat a very healthy high fiber diet (50g+) with a lot of prebiotics/probiotics/postbiotics both natural and in capsules, so I’m sure that’s helping a lot as well as the bovine and sheep colostrum I also take daily.”
5/5 Bloating & gas“Organ meats, like pancreas, gallbladder, and also colostrum are so amazing for gut health.”
5/5“Colostrum was a game changer for me.”
1/5 Side effects“I tried sundiber, colostrum- made things worse.”
2/5 Side effects“When I was carnivore and was taking colostrum powder (1/4 tsp daily) and possibly had sibo the whole time, I couldn't tolerate dairy at first, but over time with the addition of colostrum I was able to tolerate cream without it sending me to the toilet.”
4/5“Man colostrum has done wonders for me!!!”
4/5“what worked for me was taking AMRA COLOSTRUM.”
4/5“Colostrum supposedly helps rebuild the foundation of the gut by giving all the things that establishes our guts when we’re babies to be able to handle digestion.”
4/5“Colostrum can really help some people with symptoms but I don't think it keeps the underlying microbial issues from continuing to proliferate -- it binds to some of the toxins produced by them to reduce symptoms (and it's more effective on an empty stomach).”
4/5“Beano definitely helps, and I ended up using colostrum.”
4/5“recommended it for me in lieu of colostrum which he has also been recommending for years prior to kepos coming into existence - and I’m an active SIBO patient”
4/5“Honestly, the only things that have worked for me is dried prunes daily, digestive stretches, yogurt with colostrum once a day, and a cup of hot water in the morning.”
4/5 Bloating & gasCost“Lol it was a nightmare, I finally got relief from my massage therapist, she recommended colostrum which worked for the diarrhea, and the pain.”
4/5“I have to take molybdenum glycinate with each dose to tolerate colostrum because it’s high in sulfur.”
3/5“I am not affiliated, do not benefit or anything from this company, but I have to admit I swear by Armra colostrum.”
4/5“I had a stomach lining issue and have been taking colostrum before bed every night and I think it is helping.”
4/5 Cost“I'm trying colostrum now but the good stuff is very expensive.”
2/5 Bloating & gasSide effects“I've dealt with gut issues for a long time and tried a lot over the years like probiotics, herbal stuff, colostrum, different prebiotics and most of them made things worse honestly, the last thing I tried was kepos and I'm still taking it,…”
4/5“colostrum is a comer - more info coming out all the time on it.”
3/5“They had no solutions so I found the colostrum info on my own as I had taken it with some success but when the doctors could nor help, I was at my wit's end.”
4/5“Anyhow, got lucky found a doctor that did prescribe it and combined with low FODMAP, Colostrum, zinc-carosine (good for gut-lining repair it seems) helped me a lot but caught Covid shortly after which messed things up again.”
4/5“Daily Colostrum supplement really helps me!”
4/5“If it doesn't interfere with your beliefs, colostrum is excellent at repairing gut lining.”
4/5“Was not sodium butyrate, I think it was cal/mag butyrate but that stuff I found to wirk even better than igG or in my case looking back igG was actually not the heavy hitter I thought—I took Ortho Molecular product with igG and colostrum…”
4/5“So I have cut out trigger foods for me, focusing on high fiber/5 a day for biome diversity, collagen, colostrum, foods that help the mucosal lining, clean products I use for my home/body, foods that support my liver, deep breathing/somatic…”
4/5“On a side note, one of the best things to help repair my gut has been colostrum.”
2/5“im taking colostrum now, probably going to step up to SBI, l-glutamine did nothing for my secratory igA, colostrum binds LPS as well and binds iron to stop gram negatives from using it as their fuel source.”
4/5“Colostrum definitely helps me out. I felt a slight die off from it”
4/5“So I know this post is old but colostrum powder helps get rid of the bad breath smell it worked for me!”
4/5“Colostrum + zinc-carnosine +probiotics worked for me.”
These are examples of Bovine colostrum products sold on Amazon. They are not ranked by Reddit and the score above is for the ingredient, not a specific product. Check the label for dose and other ingredients.
Published studies (we list them so you can read the evidence yourself; inclusion is not an endorsement):
Across 80 Reddit comments from people who say they have used it, 28 of 37 rated comments were positive and 6 negative, for a GutVerdict score of 3.6/5. These are self-reported experiences, not clinical evidence.
3 of 37 rated owner comments (8%) describe an unwanted effect such as gas, bloating or an upset stomach. Check the safety notes on this page and ask a doctor or pharmacist before starting.
Most rated owner comments come from people in r/SIBO and others who mention SIBO (21 comments, 16 positive).
No. The score summarizes Reddit owner comments only. Factual statements on this page link to NIH or PubMed sources, and nothing here is medical advice.
“My condition improved when I started to take Glutamine in the morning and one banana before bed.”
What owners report →
“Also one that helped me butyrate in form of tributrin”
What owners report →
“Yes...zinc carnosine has been a gamechanger for me.”
What owners report →Comparisons: L-glutamine vs Bovine colostrum
Last updated 2026-11-03. Mentions scanned: 337 in 242 threads.